1-BCP

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. 1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [³H]NE release in rat hippocampal slices.
   Desai et al.
   Neuropharmacology, 1995;34:141
3. A centrally active drug that modulates AMPA receptor gated currents.
   Arai et al.
   Brain Res., 1994;638:343
4. AMPA receptor activation potentiated by the AMPA modulator 1-BCP is toxic to cultured rat hippocampal neurons.
   Yamada et al.
   Neurosci.Lett., 1998;249:119
5. Effects of AMPA receptor positive modulators on amphetamine- and dizocilpine-induced locomotion.
   Vanove
   Eur.J.Pharmacol., 1997;332:115

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