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R&D Systems Enzymes
What is an Enzyme?
Enzymes are catalysts and function by lowering the activation energy of a reaction resulting in an increase in reaction rate. Enzymes are present in all living organisms and are essential to maintaining life. These macromolecules, the vast majority being proteins, catalyze over 5000 different biochemical reactions in cells. For example, metabolic pathways are comprised of a series of enzymes that speed up chemical reactions by several orders of magnitude. These enzyme pathways continually accomplish very complex chemical reactions inside every living cell. The history of enzymes dates to the 18th and early 19th centuries. The concept was first used to explain digestion, conversion of starch to sugars, and fermentation of sugar to alcohol. The term “enzyme” was first coined by German physiologist Wilhelm Kuhne in 1877. Today, in addition to life science research, enzymes are used in the agricultural, food, pharmaceutical, and cosmetic industries. In the pharmaceutical industry, enzymes are used in drug manufacturing, and many drugs are enzyme inhibitors that act by binding to an enzyme and blocking its activity by interfering with substrate binding.
About R&D Systems Enzymes
R&D Systems offers over 800 active enzymes that can be used in a variety of biological reactions and in many different applications. Our enzymes have been selected for high activity and QC tested to ensure lot-to-lot consistency and stability. We offer many recombinant enzymes produced in controlled systems to ensure lot-to-lot consistency. With over 30 years of experience offering enzymes to the research community, we continually strive to produce enzymes with the highest purity and performance.
Enzymes for bioprocessing applications enable the rapid completion of a chemical process in a specific, controlled environment. Bioprocessing enzymes are essential tools for basic scientific research. In addition, they are used in the production of pharmaceuticals, foods, chemicals, and fuels.
Recent successes with FDA approved immunotherapies have greatly increased interest in the field. Several immunotherapies are some of the most promising anticancer treatments. Recently, focus on metabolism in the tumor microenvironment has intensified due to its modulatory effect on immune recognition and role in elimination of tumor cells.
Metabolic enzymes help carry out essential cellular functions necessary to maintain survival, growth, and homestatsis. These enzymes include kinases, dehydrogenases, lyases, oxygenases, reductases, phosphatases, carboxylases, and transferases and cover a wide range different enzymatic functions. Many common diseases have a metabolic component including diabetes, cancer, obesity, and hypertension.
PRODUCT AVAILABILITY: Update Regarding the Evolving COVID-19 Situation
Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.