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Acipimox

Catalog #: 2784 Datasheet / COA / SDS

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2784 has been discontinued.
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Acipimox | CAS No. 51037-30-0 | Additional Lipid Metabolism Compounds
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Description: Antilipolytic agent

Chemical Name: 5-Methyl-4-oxide-2-pyrazinecarboxylic acid

Purity: ≥99%

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Biological Activity

Acipimox is a antilipolytic agent; lowers plasma free fatty acid (FFA), triglyceride (TG), glucose and insulin levels and increases leptin levels.

Technical Data

M.Wt:
154.12
Formula:
C6H6N2O3
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
51037-30-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Acipimox stimulates leptin production from isolated rat adipocytes.
    Wang-Fisher et al.
    J.Endocrinol., 2002;174:267
  2. Pharmacological proflie of a new antilipolytic agent: 5-methyl-pyrazine-2-carboxylic acid 4-oxide (acipimox) II - Antilipolytic and blood lipid lowering activitiy
    Lovisolo et al.
    Pharmacol.Res.Comms., 1981;13:163
  3. Mechanism of anti-lipolytic action of acipimox in isolated rat adipocytes.
    Christie et al.
    Diabetol., 1996;39:45

Product Datasheets

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