Benidipine hydrochloride

Tocris Bioscience | Catalog # 3934

Non-selective Cav blocker; also mineralocorticoid receptor antagonist
Tocris Bioscience
Discontinued Product
3934 has been discontinued. View all Non-selective Cav Blockers products.

Key Product Details

Description

Non-selective Cav blocker; also mineralocorticoid receptor antagonist

Alternative Names

KW 3049
View all Non-selective Cav Blockers »

Product Description

Orally active antihypertensive agent which displays a wide range of activities in vitro and in vivo. Inhibits L-, N- and T-type Ca2+ channels. Also inhibits aldosterone-induced mineralocorticoid receptor activation. Exhibits cardioprotective and antiartherosclerotic effects.

Product Specifications for Benidipine hydrochloride

Molecular Weight

542.02

Formula

C28H31N3O6.HCl

Storage

Desiccate at RT

Purity

≥99% (HPLC)

Chemical Name

(4R)-rel-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-methyl 5-[(3R)-1-(phenylmethyl)-3-piperidinyl] ester hydrochloride

CAS Number

91599-74-5

PubChem ID

76968919

InChI Key

SPMJXDRNJQIBTB-IMEZZWDRSA-N

SMILES

CC1=C(C(OC)=O)[C@@H]([C@]2=CC([N+]([O-])=O)=CC=C2)C(C(O[C@H]3CN(CC4=CC=CC=C4)CCC3)=O)=C(C)N1.CC5=C(C(OC)=O)[C@H]([C@]6=CC([N+]([O-])=O)=CC=C6)C(C(O[C@@H]7CN(CC8=CC=CC=C8)CCC7)=O)=C(C)N5.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 40.65 75
Ethanol 5.42 10

Preparing Stock Solutions for Benidipine hydrochloride

The following data is based on the product molecular weight 542.02.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.75 mM 2.46 mL 12.30 mL 24.60 mL
3.75 mM 0.49 mL 2.46 mL 4.92 mL
7.5 mM 0.25 mL 1.23 mL 2.46 mL
37.5 mM 0.05 mL 0.25 mL 0.49 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

Product Documents for Benidipine hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Benidipine hydrochloride

For research use only

Related Research Areas

Ion Channels and Regulators

Citations for Benidipine hydrochloride

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