CD 437

Tocris Bioscience | Catalog # 1549

RARγ-selective agonist
Tocris Bioscience
Discontinued Product
1549 has been discontinued. View all Retinoic Acid Receptor Agonists products.

Key Product Details

Description

RARγ-selective agonist

Alternative Names

AHPN

Product Description

CD 437 is a synthetic retinoid that is an RARγ-selective agonist. Displays RARγ-dependent and -independent effects on differentiation and apoptosis.

Product Specifications for CD 437

Molecular Weight

398.50

Formula

C27H26O3

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

6-(4-Hydroxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid

CAS Number

125316-60-1

PubChem ID

135411

InChI Key

LDGIHZJOIQSHPB-UHFFFAOYSA-N

SMILES

OC(=O)C1=CC=C2C=C(C=CC2=C1)C1=CC=C(O)C(=C1)C12CC3CC(CC(C3)C1)C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 39.85 100
Ethanol 7.97 20

Preparing Stock Solutions for CD 437

The following data is based on the product molecular weight 398.50.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.51 mL 12.55 mL 25.09 mL
5 mM 0.50 mL 2.51 mL 5.02 mL
10 mM 0.25 mL 1.25 mL 2.51 mL
50 mM 0.05 mL 0.25 mL 0.50 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 23 publications citing the usage of this product.

Product Documents for CD 437

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CD 437

For research use only

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