Cyclofenil
Discontinued Product
Chemical Name: 4,4'-(Cyclohexylidenemethylene)bisphenol 1,1'-diacetate
Purity: ≥99%
Biological Activity
Non-steroidal selective estrogen receptor modulator (SERM). Displays higher affinity for estrogen receptor β (ERβ) than for ERα.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Characterization of the pharmacore properties of novel selective estrogen receptor downregulators (SERDs).
Kieser et al.
J.Med.Chem., 2010;53:3320 -
Fluorine-substituted cyclofenil derivatives as estrogen receptor ligands: synthesis and structure-affinity relationship study of potential PET agents for imaging estrogen receptors in breast cancer.
Seo et al.
J.Med.Chem., 2006;49:2496
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