FBXO45 Antibody (RB53750)

Novus Biologicals | Catalog # NBP3-52174

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG Clone # RB53750
View all FBXO45 Primary Antibodies »

Product Specifications

Immunogen

This FBXO45 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 83-115 amino acids from human FBXO45.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FBXO45 Antibody (RB53750)

FBXO45 Antibody (RB53750)

Western Blot:FBXO45 Antibody (RB53750)[NBP3-52174]-

Anti-FBXO45 Antibody (N-Term)at 1:2000 dilution + HT-1080 whole cell lysatesLysates/proteins at 20 �g per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 31 kDaBlocking/Dilution buffer: 5% NFDM/TBST.

Applications for FBXO45 Antibody (RB53750)

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FBXO45

F-box/SPRY domain-containing protein 1, also known as F-box only protein 45 and FBXO45, is a component of the E3 ubiquitin ligase complex. FBXO45 is required for normal neuromuscular synaptogenesis, neuronal migration and axon pathfinding. FBXO45 also plays a role in regulating neurotransmission by mature neurons and controlling synaptic activity via UNC13A in the ubiquitin dependent pathway. FBXO45 protein recognizes TP73 and promotes it ubiquitination and degradation. FBXO45 expression is down regulated in response to DNA damage.

Alternate Names

F-box only protein 45, F-box protein 45, F-box/SPRY domain-containing protein 1, Fbx45

Gene Symbol

FBXO45

Additional FBXO45 Products

Product Documents for FBXO45 Antibody (RB53750)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for FBXO45 Antibody (RB53750)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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