LY 215840

Tocris Bioscience | Catalog # 1523

5-HT2/5-HT7 antagonist
Tocris Bioscience
Discontinued Product
1523 has been discontinued. View all Non-selective 5-HT Receptor Antagonists products.

Key Product Details

Description

5-HT2/5-HT7 antagonist
View all Non-selective 5-HT Receptor Antagonists »

Product Description

LY 215840 is a 5-HT2/5-HT7 receptor antagonist. Reduces stimulatory effect of serotonin on aldosterone secretion; also reduces 5-HT-induced cAMP formation (pKB = 8.26).

Product Specifications for LY 215840

Molecular Weight

395.54

Formula

C24H33N3O2

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

[8β(1S,2R)]-N-(2-Hydroxycyclopentyl)-6-methyl-1-(1-methylethyl)-ergoline-8-carboxamide

CAS Number

137328-52-0

PubChem ID

9822062

InChI Key

IMSDOBUYDTVEHN-ILMFXRJHSA-N

SMILES

CC(C)N2C1=C(C(C[C@]4([H])[C@@]([H])3C[C@@H]([C@@](N[C@@H]5[C@H](O)CCC5)=O)CN4C)=C2)C3=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 39.55 100
Ethanol 9.89 25

Preparing Stock Solutions for LY 215840

The following data is based on the product molecular weight 395.54.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.53 mL 12.64 mL 25.28 mL
5 mM 0.51 mL 2.53 mL 5.06 mL
10 mM 0.25 mL 1.26 mL 2.53 mL
50 mM 0.05 mL 0.25 mL 0.51 mL

Calculators

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Product Documents for LY 215840

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for LY 215840

For research use only

Customer Reviews for LY 215840 (1)

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  • 5-HT has a potential for relaxant
    Name: Anonymous
    Species: Rat
    Assay Type: In Vivo
    Verified Customer | Posted 02/18/2020
    1nM 5-HT7 receptor antagonists LY215840
    LY 215840 1523

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