Mephenytoin

Key Product Details

Product Description

Mephenytoin is a CYP2C19 and CYP2B6 substrate. Anticonvulsant.

Product Specifications for Mephenytoin

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Mephenytoin

The following data is based on the product molecular weight 218.25.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.2 mM	22.91 mL	114.55 mL	229.10 mL
1 mM	4.58 mL	22.91 mL	45.82 mL
2 mM	2.29 mL	11.45 mL	22.91 mL
10 mM	0.46 mL	2.29 mL	4.58 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Foti CYP2C19 inhibition: the impact of substrate probe selection on in vitro inhibition profiles. Drug Meta. Dispos. 2008 PMID: 18048485
• Tamminga Mephenytoin as a probe for CYP2C19 phenotyping: effect of sample storage, intra-individual reproducibility and occurrence of adverse events. Br.J.Clin.Pharmacol. 2001 PMID: 11422005
• Knabe and Wunn Racemic and optically active hydantoins from disubstituted cyanoacetic acids. Arch.Pharmacol.

Product Documents for Mephenytoin