Ocinaplon

Key Product Details

Product Description

Ocinaplon is a modulator of GABA_A receptors. Displays modest selectivity for GABA_A α₁ receptors; displays partial agonist activity at α2-, α3- and α5-containing receptors. Exhibits anxiolytic activity.

Product Specifications for Ocinaplon

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Ocinaplon

The following data is based on the product molecular weight 301.30.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.32 mL	16.59 mL	33.19 mL
5 mM	0.66 mL	3.32 mL	6.64 mL
10 mM	0.33 mL	1.66 mL	3.32 mL
50 mM	0.07 mL	0.33 mL	0.66 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Lippa Selective anxiolysis produced by ocinaplon, a GABA_A receptor modulator. Proc.Natl.Acad.Sci.USA 2005 PMID: 15870187
• Rupprecht GABA_A receptors as targets for novel anxiolytic drugs. World J.Biol.Psychiatry 2006 PMID: 17071543
• Mirza Comparative cue generalization profiles of L-838,417, SL651498, zolpidem, CL218,872, ocinaplon, bretazenil, ZopiC., and various benzodiazepines in chlordiazep. and zol. drug discrimination. J.Pharmacol.Exp.Ther. 2006 PMID: 16339395

Product Documents for Ocinaplon