PE 154

Key Product Details

Product Description

PE 154 is a potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC₅₀ values are 280 pM and 16 nM respectively). Targets and labels β-amyloid plaques in histochemical analysis.

Product Specifications for PE 154

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for PE 154

The following data is based on the product molecular weight 589.68.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	3.39 mL	16.96 mL	33.92 mL
2.5 mM	0.68 mL	3.39 mL	6.78 mL
5 mM	0.34 mL	1.70 mL	3.39 mL
25 mM	0.07 mL	0.34 mL	0.68 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

• Elsinghorst A gorge-spanning, high-affinity cholinesterase inhibitor to explore β-amyloid plaques. Org.Biomol.Chem. 2009 PMID: 19763296
• Kacza In vivo labelling of hippocampal beta-amyloid in triple-transgenic mice with a fluorescent acetylcholinesterase inhibitor released from nanoparticles. Eur.J.Neurosci. 2010 PMID: 20092557

Product Documents for PE 154