Prochlorperazine dimaleate

Key Product Details

Product Description

D₂ receptor antagonist. Also interacts with 5-HT₃ and nAChR. Displays antipsychotic, antispasmodic, antiemetic and antinociceptive activity in vivo.

Product Specifications for Prochlorperazine dimaleate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Prochlorperazine dimaleate

The following data is based on the product molecular weight 606.09.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.25 mM	6.60 mL	33.00 mL	66.00 mL
1.25 mM	1.32 mL	6.60 mL	13.20 mL
2.5 mM	0.66 mL	3.30 mL	6.60 mL
12.5 mM	0.13 mL	0.66 mL	1.32 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Ghelardini Prochlorperazine induces central antinociception mediated by the muscarinic system. Pharmacol.Res. 2004 PMID: 15225680
• Satoh The antipsychotic and antiemetic drug prochlorper. delays the ventricular repolarization of the in situ canine heart. J.Pharm.Sci.
• Lummis and Baker Radioligand binding and photoaffinity labeling studies show a direct interaction of phenothiazenes at 5-HT₃ receptors. Neuropharmacology 1997 PMID: 9225292

Product Documents for Prochlorperazine dimaleate