Product Description
Qc 1 is a reversible, non-competitive inhibitor of threonine dehydrogenase (TDH) (IC50 ~500 nM). Induces autophagy and inhibits cell proliferation in mouse embryonic stem (ES) cells.
Product Specifications for Qc 1
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 22.77 | 50 |
Preparing Stock Solutions for Qc 1
The following data is based on the product molecular weight 455.45.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 4.39 mL | 21.96 mL | 43.91 mL |
| 2.5 mM | 0.88 mL | 4.39 mL | 8.78 mL |
| 5 mM | 0.44 mL | 2.20 mL | 4.39 mL |
| 25 mM | 0.09 mL | 0.44 mL | 0.88 mL |
Calculators
Background References
References are publications that support the biological activity of the product.
- Alexander Targeted killing of a mammalian cell based upon its specialized metabolic state. Proc.Natl.Acad.Sci.USA 2011 PMID: 21896756
Product Documents for Qc 1
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Qc 1
For research use only
Related Research Areas
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