(R)-Modafinil

Tocris Bioscience | Catalog # 6131

Dopamine uptake inhibitor
Tocris Bioscience
Discontinued Product
6131 has been discontinued. View all Dopamine Transporter Inhibitors products.

Key Product Details

Description

Dopamine uptake inhibitor

Alternative Names

armodafinil

Product Description

(R)-Modafinil is a dopamine uptake inhibitor (IC50 = 4 μM). Increases extracellular dopamine (DA) levels in the nucleus accumbens and substitutes for cocaine in discrimination tests in mice.

Product Specifications for (R)-Modafinil

Molecular Weight

273.35

Formula

C15H15NO2S

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

(-)-2R-[(Diphenylmethyl)sulfinyl]acetamide

CAS Number

112111-43-0

PubChem ID

9690109

InChI Key

YFGHCGITMMYXAQ-LJQANCHMSA-N

SMILES

O=[S@](CC(N)=O)C(C1=CC=CC=C1)C2=CC=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 27.34 100
Ethanol 5.47 20

Preparing Stock Solutions for (R)-Modafinil

The following data is based on the product molecular weight 273.35.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.66 mL 18.29 mL 36.58 mL
5 mM 0.73 mL 3.66 mL 7.32 mL
10 mM 0.37 mL 1.83 mL 3.66 mL
50 mM 0.07 mL 0.37 mL 0.73 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for (R)-Modafinil

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (R)-Modafinil

For research use only

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