RI 1

Key Product Details

Product Description

RI 1 is a RAD51 inhibitor (IC₅₀ is in the range 5 - 30 μM). Covently binds C139 on protein surface. Inhibits homologous recombination. Cell permeable. Sensitizes tumor cells to chemotherapy.

Product Specifications for RI 1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for RI 1

The following data is based on the product molecular weight 361.61.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.77 mL	13.83 mL	27.65 mL
5 mM	0.55 mL	2.77 mL	5.53 mL
10 mM	0.28 mL	1.38 mL	2.77 mL
50 mM	0.06 mL	0.28 mL	0.55 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Budke RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells. Nucleic Acids Res. 2012 PMID: 22573178

Product Documents for RI 1