T-peptide

Tocris Bioscience | Catalog # 6726

Cytotoxic Tau peptide; cell permeable
Tocris Bioscience
Discontinued Product
6726 has been discontinued. View all Microtubule Binding Compounds products.

Key Product Details

Description

Cytotoxic Tau peptide; cell permeable
View all Microtubule Binding Compounds »

Product Description

T-peptide is a peptide derived from microtubule binding repeat of Tau protein. Self-assembles into 30-55 nm paired helical filaments (PHFs) even in the absense of inducers. Cytotoxic in multiple cell lines including cortical neurons, cerebellar granular neurons, neuroblastoma cells, kidney fibroblasts and HEK293 cells. Co-localizes with pathological hyperphosphorylated forms of tau in vitro. Cell permeable.

Product Specifications for T-peptide

Molecular Weight

2195.66

Formula

C92H171N45O18

Storage

Store at -20°C

CAS Number

2022956-62-1

SMILES

[H]N([C@H](C(C)C)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CC1=CC=C(O)C=C1)C(=O)N[C@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O)C(C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 2mg/ml in water

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Background References

References are publications that support the biological activity of the product.

Product Documents for T-peptide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for T-peptide

For research use only

Related Research Areas

Microtubules

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