Taurine
Tocris Bioscience | Catalog # 0209
Key Product Details
Description
Product Description
One of the most abundant free amino acids in the brain. A partial agonist at the inhibitory glycine receptor. May be used in protocols for the generation of retinal pigment epithelial cells from hPSCs. Taurine-fed middle-aged mice have improved functioning of bone, muscle, pancreas, brain, fat, gut, and immune system, and a longer life span. It reduces cellular senescence, protected against telomerase deficiency, suppressed mitochondrial dysfunction, decreased DNA damage, and attenuated inflammation. Taurine supplementation increases health span and life span in worms and health span in non-human primates.
Product Specifications for Taurine
Molecular Weight
Formula
Storage
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 12.51 | 100 |
Preparing Stock Solutions for Taurine
The following data is based on the product molecular weight 125.14.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 7.99 mL | 39.96 mL | 79.91 mL |
| 5 mM | 1.60 mL | 7.99 mL | 15.98 mL |
| 10 mM | 0.80 mL | 4.00 mL | 7.99 mL |
| 50 mM | 0.16 mL | 0.80 mL | 1.60 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 12 publications citing the usage of this product.
- Singh Taurine deficiency as a driver of aging. Science 2023 PMID: 37289866
- Surendran An improved protocol for generation and characterization of human-induced pluripotent stem cell-derived retinal pigment epithelium cells STAR Protoc. 2022 PMID: 36386870
- Schmieden and Betz Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol.Pharmacol. 1995 PMID: 7476923
- Palmi Potentiation of mitochondrial Ca2+ sequestration by taurine. Biochem.Pharmacol. 1999 PMID: 10484070
- Chung Saturable disposition of taurine in the rat cerebrospinal fluid. J.Pharmacol.Exp.Ther. 1996 PMID: 8632336
- Boldyrev Carnosine and taurine protect rat cerebellar granular cells from free radical damage. Neurosci.Lett. 1999 PMID: 10213162
Product Documents for Taurine
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Taurine
For research use only
Related Research Areas
Citations for Taurine
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