Thalidomide 4'-oxyacetamide-alkylC8-amine

Tocris Bioscience | Catalog # 6946

Cereblon ligand with alkyl linker and terminal amine for onward chemistry
Tocris Bioscience

Key Product Details

Description

Cereblon ligand with alkyl linker and terminal amine for onward chemistry
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Product Description

Thalidomide 4'-oxyacetamide-alkylC8-amine is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

This product has been recently renamed. The previous name for this product was Thalidomide amide-alkylC8-amine

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PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Product Specifications for Thalidomide 4'-oxyacetamide-alkylC8-amine

Molecular Weight

494.97

Formula

C23H30N4O6.HCl

Storage

Desiccate at RT

Purity

≥95% (HPLC)

Chemical Name

N-(8-Aminooctyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-acetamide hydrochloride

CAS Number

2415263-07-7

PubChem ID

146018961

InChI Key

KPPZEDZTBDIUJN-UHFFFAOYNA-N

SMILES

NCCCCCCCCNC(COC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O)=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

References are publications that support the biological activity of the product.

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Product Documents for Thalidomide 4'-oxyacetamide-alkylC8-amine

Certificate of Analysis

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Product Specific Notices for Thalidomide 4'-oxyacetamide-alkylC8-amine

For research use only

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