Using Antibody Arrays for Assessing the Integration of Multiple Signaling Pathways and Off-Target Inhibitors
by Greta Wegner, Erin Eleria, Jackie Ernst, & Amy James.
Scientific Meeting PostersThe Problem: Time-consuming Western blots
- Assessing phosphorylation changes in multiple interrelated pathways
- Performing pharmacological screens in a timely manner
- Identifying off-target pharmacological effects
The Solution: Proteome Profiler™ Phospho-Antibody Arrays
- Easier to perform than a Western blot
- Uncover new relationships between signaling pathways
- Identify off-target pharmacological responses that can confound results and waste time
- Collect data from the array membrane in the same manner as an immunoblot
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