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4EBP1 Products

The eukaryotic initiation factor 4E binding protein 1, also known as PHAS-1 (phosphorylated heat and acid stable protein regulated by insulin 1) binds to eIF-4E to prevent translation initiation. Upon phosphorylation by the target of rapamycin (TOR) kinase, 4E-BP1 releases eIF-4E and translation initiation ensues.