BLAME/SLAMF8 Proteins and Enzymes

BLAME, also known as Signaling Lymphocyte Activation Molecule Family Member 8 (SLAMF8), is an Ig superfamily protein that is a member of the SLAM/CD150/CD2 family of receptors. It is expressed on macrophages and dendritic cells. BLAME modulates signaling through the B cell receptor and may also function during B lineage commitment.