1 result for "MDM2/HDM2" in 产品

MDM2/HDM2 Products

MDM2 is a key regulator of p53 tumor suppressor protein activity and stability. MDM2 binds to and inhibits the transactivation domain of p53. In addition, MDM2 controls p53 stability by functioning as its E3 ligase in ubiquitination and by shuttling p53 from the nucleus to the cytoplasm for subsequent degradation. The importance of the p53/MDM2 rel...

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Reactivity: Human
Details: Mouse IgG1 kappa Monoclonal Clone #1A7
Applications: IHC, WB, ELISA, Func, Mycoplasma
Western Blot: MDM2/HDM2 Antibody (1A7) [H00004193-M01]
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