Cardionogen 1

Tocris Bioscience | Catalog # 4475

Inhibitor of Wnt/β-catenin signaling
Tocris Bioscience
Discontinued Product
4475 has been discontinued. View all beta-Catenin Inhibitors products.

Key Product Details

Description

Inhibitor of Wnt/β-catenin signaling

Product Description

Cardionogen 1 is a wnt signaling modulator. Potently inhibits Wnt/β-catenin-dependent transcription in murine ES cells (EC50 = 23 nM) and zebrafish embryos. Enlarges heart size via cardiomyocyte hyperplasia; induces ES cell cardiac differentiation.

Product Specifications for Cardionogen 1

Molecular Weight

274.34

Formula

C13H14N4OS

Storage

Store at +4°C

Purity

≥99% (HPLC)

Chemical Name

6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole

CAS Number

577696-37-8

PubChem ID

663145

InChI Key

SWTUPSNBTSPBIH-UHFFFAOYSA-N

SMILES

C12=NN=C(C3=CC=CO3)N1N=C(C4CCCCC4)S2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 5.49 20
Ethanol 2.74 10

Preparing Stock Solutions for Cardionogen 1

The following data is based on the product molecular weight 274.34.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 18.23 mL 91.13 mL 182.26 mL
1 mM 3.65 mL 18.23 mL 36.45 mL
2 mM 1.82 mL 9.11 mL 18.23 mL
10 mM 0.36 mL 1.82 mL 3.65 mL

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Background References

References are publications that support the biological activity of the product.

Product Documents for Cardionogen 1

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Cardionogen 1

For research use only

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