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Cystamine dihydrochloride

Catalog #: 4981 Datasheet / COA / SDS

Discontinued Product

4981 has been discontinued.
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Cystamine dihydrochloride | CAS No. 56-17-7 | Other Transferase Inhibitors
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Description: Transglutaminase inhibitor; neuroprotective

Chemical Name: 2,2'-Diaminodiethyl disulfide dihydrochloride

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Biological Activity

Cystamine dihydrochloride is a transglutaminase inhibitor. Attenuates cell death induced by 3-nitropropionic acid (Cat. No. 4849) in Huntington's disease (HD) striatal cells. Also decreases aggregated and cross-linked huntingtin in transfected cells, and increases brain levels of BDNF. Shown to extend survival and improve motor performance in transgenic HD mice. Neuroprotective.

Technical Data

M.Wt:
225.2
Formula:
C4H12N2S2.2HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Storage:
Desiccate at RT
CAS No:
56-17-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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