NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity. NMDARs are heteromeric complexes of multiple subunits: NR1, which occurs as eight distinct isoforms as the result of alternate splicing; NR2 (NR2A, B, C and D are encoded by four related genes, several of which also display multiple splice forms); and NR3 (NR3A and B also have several splice forms). The particular combination of subunits determines the functional characteristics of the receptor.
Human/Mouse/Rat GRIN1/NMDAR1 Antibody
R&D Systems | Catalog # PPS011B
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Key Product Details
Species Reactivity
Validated:
Human, Mouse, Rat
Cited:
Mouse, Transgenic Mouse
Applications
Validated:
Western Blot, Immunoprecipitation
Cited:
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG Clone # R1JHL
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Product Specifications
Clonality
Monoclonal
Host
Mouse
Isotype
IgG
Applications for Human/Mouse/Rat GRIN1/NMDAR1 Antibody
Application
Recommended Usage
Immunoprecipitation
Western Blot
Formulation, Preparation, and Storage
Formulation
Lyophilized from cell culture media
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: GRIN1/NMDAR1
Long Name
Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate, Subunit 1
Alternate Names
GluN1, MRD8, NMD-R1, NMDA R, NR1 Subunit, NMDA1, NMDAR1
Gene Symbol
GRIN1
Additional GRIN1/NMDAR1 Products
Product Documents for Human/Mouse/Rat GRIN1/NMDAR1 Antibody
Product Specific Notices for Human/Mouse/Rat GRIN1/NMDAR1 Antibody
For research use only
Citations for Human/Mouse/Rat GRIN1/NMDAR1 Antibody
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- Immunoprecipitation Protocol
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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