IgM ELISA Development Kit

Novus Biologicals | Catalog # NBP3-11759

Novus Biologicals
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Key Product Details

Assay Range

0.2 - 200 ng/mL

Sample Type

Serum, plasma, cell culture supernatants (100 uL)

Reactivity

Human, Non-human Primate
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Product Specifications

Sample Volume Required

100 uL

Conjugate

Unconjugated

Scientific Data Images for IgM ELISA Development Kit

ELISA: IgM ELISA Development Kit [NBP3-11759]

ELISA: IgM ELISA Development Kit [NBP3-11759]

ELISA: IgM ELISA Development Kit [NBP3-11759] - Standard curve reference

Kit Contents for IgM ELISA Development Kit

  • ALP-conjugated detection mAb (MT22)
  • Capture mAbs (MT11/12)
  • Human IgM ELISA standard
  • Standard reconstitution buffer

Preparation and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: IgM

IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to its large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to its high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. IgM measurement yields information about the body's immediate resistance and response to infection as well as information related to specific diseases. Decreased levels are associated with immune deficiency states, hereditary deficiencies, and myeloma. Increased levels can be associated with Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease.

Long Name

Immunoglobulin M

Alternate Names

AGM1, DKFZp686I15196, DKFZp686I15212, FLJ00385, immunoglobulin heavy constant mu, MGC104996, MGC52291, MU, VH

Gene Symbol

IGHM

Additional IgM Products

Product Documents for IgM ELISA Development Kit

Certificate of Analysis

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Product Specific Notices for IgM ELISA Development Kit

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.

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