CRBN: Products

Cereblon ligand with amine on C5 for onward chemistry

Functionalized cereblon ligand for generating Degrader negative controls; also used as Pomalidomide negative control

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Functionalized cereblon ligand for PROTAC development

High affinity fluorescent probe for TR-FRET cereblon binding assay

Cereblon ligand with terminal amine for onward chemistry

Piperazine-functionalized cereblon ligand for PROTAC development

BET bromodomain Degrader (PROTAC®); also potent Hedgehog pathway inhibitor

Aurora A Degrader (PROTAC®)

Molecular glue; induces degradation of NQAT1

Potent covalent inhibitor of Cereblon

Functionalized cereblon ligand for PROTAC development

Stable cereblon ligand, for PROTAC synthesis

Cereblon ligand with piperidine linker and terminal acid for onward chemistry

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Functionalized cereblon ligand for PROTAC development

Functionalized cereblon ligand for PROTAC development

Cereblon ligand with terminal piperidine for onward chemistry

Functionalized cereblon ligand for PROTAC development

Potent hematopoietic prostaglandin D2 synthase Degrader (PROTAC®)

Negative control for PROTAC®(H-PGDS)-7 (Cat. No. 8004)

α-synuclein Degrader (PROTAC®)

Selective STING Degrader (PROTAC®)

Negative control for STING Degrader SP23 (Cat. No. 8053)

BRG1/SMARCA4 Degrader (PROTAC®)

Potent and selective AR and AR L702H Degrader, orally bioavailable

Cereblon ligand with terminal piperazine for onward chemistry

Potent and selective BTK Degrader (PROTAC®)

Potent BTK Degrader (PROTAC®)