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Keap1 Products

Keap1 is a member of the Kelch family of proteins. Keap1 contains an N-terminal BTB/POZ domain that mediates homodimerization. When dimerized, six Kelch repeats on the extended C-terminus interact with and inactivate Nrf2, a potent transcriptional activator of detoxifying enzymes, providing a homeostatic brake on oxidative stress activity.

Reactivity: Human, Mouse, Rat
Details: Mouse IgG2B Monoclonal Clone #333116
Applications: KO, WB, Simple Western
Detection of Human/Mouse/Rat Keap1 antibody by Western Blot.
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