1-BCP (CAS 34023-62-6): R&D Systems
Catalog Number: 1048
Chemical Name: 1-(1,3-Benzodioxol-5-ylcarbonyl)piperidine
Biological Activity
A centrally active selective potentiator of AMPA-mediated responses. Facilitates memory retention in rats.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. A centrally active drug that modulates AMPA receptor gated currents.
    Arai et al.
    Brain Res., 1994;638:343
  2. 1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [3H]norepinephrine release in rat hippocampal slices.
    Desai et al.
    Neuropharmacology, 1995;34:141
  3. AMPA receptor activation potentiated by the AMPA modulator 1-BCP is toxic to cultured rat hippocampal neurons.
    Yamada et al.
    Neurosci.Lett., 1998;249:119
  4. Effects of AMPA receptor positive modulators on amphetamine- and dizocilpine-induced locomotion.
    Eur.J.Pharmacol., 1997;332:115

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