With over 30 years of experience developing and manufacturing recombinant proteins for cytokine and growth factor research, our stringent purification and production standards ensure that our proteins display the highest levels of bioactivity and purity, low endotoxin levels, and lot-to-lot consistency.
Manufactured under guidelines that allow for their use as ancillary materials in cell therapy or further manufacturing processes, GMP-grade cytokines and growth factors come with extensive documentation to provide cell therapy researchers with a consistent, fully transparent, and traceable source of reagents.
Take advantage of our wide range of bioactive recombinant immune checkpoint proteins. From common targets like PD-L1 and CTLA-4 to emerging targets such as butyrophilins and LILRB receptors, we offer a variety of tags and species for studying immune checkpoints.
Explore our expanding catalog of Avi-tag biotinylated proteins. These proteins are enzymatically biotinylated at a single site within the Avi-tag, providing consistent labeling, uniform protein orientation, and the same high level of bioactivity as the unlabeled protein.
From proteases and bioprocessing enzymes to glycobiology- and ubiquitin-related enzymes, we offer a large selection of enzymes for various applications. Additionally, we provide a range of enzyme inhibitors, substrates, and enzyme activity kits to further your research.
Reduce aliquoting with our single-use vials of lyophilized ProDots proteins. ProDots proteins are R&D Systems proteins packaged into easy-to-use balls that can be rolled into cell culture media to reduce media preparation time and ensure optimal protein recovery and bioactivity.
If you don’t see what you need listed on our website, contact us. From scratch protein development to customizing a protein that we already offer, our custom services team will create the protein that fits your experimental needs.
Are you in need of large quantities of a particular protein? Contact us for a bulk quote. We have the capacity and expertise to scale up the production of any protein to meet your needs, and we offer economical pricing on bulk orders.
How are recombinant proteins made?
Recombinant proteins are made using an engineered DNA sequence that contains genetic instructions to synthesize the protein of interest. This DNA is delivered to a host cell where the cell’s internal machinery is used to synthesize the recombinant protein. The cells are cultured at scale to increase production, and then the recombinant protein is purified.
R&D Systems’ rich history in the recombinant protein industry began over 30 years ago. Today, we are fast approaching 5000 recombinant proteins. Our stringent quality control specifications lead to industry-leading bioactivity and lot-to-lot consistency. R&D Systems proteins are the most cited proteins in the scientific literature. Today, we continue to innovate so that we can provide the research community with the best proteins on the market.
Proteins and Enzymes Frequently Asked Questions
Unit conversion table
Bioassay Testing Services
Molarity and Reconstitution Calculators
Proteins in a Plate for High Throughput Screening