Luminex® Assays and Luminex High Performance Assays

R&D Systems offers Luminex Assays and Luminex High Performance Assays for simultaneously detecting and quantifying multiple target analytes in qualified complex sample types. Luminex bead-based multiplex assays are designed to provide accurate, reproducible results for every target analyte. They require small sample volumes, are cost-effective, and allow researchers to collect more data in less time than other assays. To view a list of analytes available in the polystyrene or magnetic bead formats for the Luminex Assays and Luminex High Performance Assays, follow the links below.


Luminex Assays

Luminex Assays are the most flexible bead-based multiplex assays that we offer. They allow up to 100 user-defined target analytes to be simultaneously profiled using cell culture supernates, serum, or plasma samples. Bring the details of your complex samples into focus.

Luminex High Performance Assays

Luminex High Performance Assays are the most accurate and precise bead-based multiplex assays for simultaneously measuring up to 45 analytes in qualified complex matrices. Trust your results with the best, most dependable assays on the market.

Luminex Instrumentation

R&D Systems Luminex Assays are compatible with all Luminex instrumentation systems. These systems can be obtained from R&D Systems.

Luminex Immunoglobulin Isotyping Assays

Luminex Immunoglobulin Isotyping Assays allow for the simultaneous quantitation of up to six immunoglobulin isotypes. Classify immunoglobulin isotypes in total, or by their kappa or lambda chains in cell culture supernates, serum, or plasma.


Principle of the Luminex Assay

Luminex Assays and High Performance Assays utilize color-coded polystyrene or superparamagnetic beads coated with analyte-specific antibodies. Beads recognizing different target analytes are mixed together and incubated with the sample. Captured analytes are subsequently detected using a cocktail of biotinylated detection antibodies and a streptavidin-phycoerythrin conjugate.

Kits are available in two formats: polystyrene or magnetic beads

  • Polystyrene beads: Polystyrene beads are designed for use with the Luminex 100™, Luminex 200™, or Bio-Rad® Bio-Plex® dual laser analyzers.
  • Magnetic beads: Magnetic beads are designed for use with the Luminex MAGPIX®, Luminex 100, Luminex 200, or Bio-Rad Bio-Plex analyzers.