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9-AC

Catalog #: 0963
2 Citations Datasheet / COA / SDS

Discontinued Product

0963 has been discontinued.
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9-AC | CAS No. 723-62-6 | Other Chloride Channel Compounds
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Description: Chloride transport inhibitor

Chemical Name: 9-Anthracenecarboxylic acid

Purity: ≥99%

Product Details
Citations (2)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

9-AC is a Cl- transport inhibitor with a moderate to strong inhibitory action on PKA activated cardiac IcI.

Technical Data

M.Wt:
222.24
Formula:
C15H10O2
Solubility:
Soluble to 10 mM in ethanol and to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
723-62-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
    Fox JT, Sakamuru S, Huang R
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
  2. Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1.
    Est?vez et al.
    Neuron, 2003;38:47
  3. Chemical probes for anion transporters of mammalian cell membranes.
    Cabantchik and Greger
    Am.J.Physiol., 1992;262:C803-C827
  4. The CFTR chloride channel of mammalian heart.
    Gadsby et al.
    Annu.Rev.Physiol., 1995;57:387
  5. Channel or transporter? The CLC saga continues.
    Pusch et al.
    Exp.Physiol., 2006;91:149

Product Datasheets

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Citations for 9-AC

The citations listed below are publications that use Tocris products. Selected citations for 9-AC include:

2 Citations: Showing 1 - 2

  1. Picrotoxin dramatically speeds the mammalian circadian clock independent of Cys-loop receptors.
    Authors: Freeman Et al.
    Online J Biol Sci  2013;110:103
  2. Hemolysis of erythrocytes by granulysin-derived peptides but not by granulysin.
    Authors: Li Et al.
    Antimicrob Agents Chemother  2005;49:388

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