9-AC

Key Product Details

Product Description

9-AC is a Cl^- transport inhibitor with a moderate to strong inhibitory action on PKA activated cardiac I_cI.

Product Specifications for 9-AC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for 9-AC

The following data is based on the product molecular weight 222.24.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.50 mL	22.50 mL	45.00 mL
5 mM	0.90 mL	4.50 mL	9.00 mL
10 mM	0.45 mL	2.25 mL	4.50 mL
50 mM	0.09 mL	0.45 mL	0.90 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Estévez Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1. Neuron 2003 PMID: 12691663
• Gadsby The CFTR chloride channel of mammalian heart. Annu.Rev.Physiol. 1995 PMID: 7539989
• Pusch Channel or transporter? The CLC saga continues. Exp.Physiol. 2006 PMID: 16179405
• Cabantchik and Greger Chemical probes for anion transporters of mammalian cell membranes. Am.J.Physiol. 1992 PMID: 1566811

Product Documents for 9-AC