9-Phenanthrol

Catalog # Availability Size / Price Qty
4999/50
Cat.No. 4999 - 9-Phenanthrol | C14H10O | CAS No. 484-17-3
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Description: Selective TRPM4 blocker

Chemical Name: 9-Hydroxyphenanthrene

Product Details
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Biological Activity

Selective TRPM4 blocker (IC50 = 20 μM in HEK293 cells). Exhibits no effect on CFTR or TRPM5 (at 0.25 and 1 mM respectively). Abolishes arrhythmias induced by hypoxia in a mouse heart model.

Technical Data

M.Wt:
194.23
Formula:
C14H10O
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage:
Store at +4°C
CAS No:
484-17-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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