Acipimox

Tocris Bioscience | Catalog # 2784

Antilipolytic agent
Tocris Bioscience
Discontinued Product
2784 has been discontinued. View all Additional Lipid Metabolism Compounds products.

Key Product Details

Description

Antilipolytic agent

Product Description

Acipimox is a antilipolytic agent; lowers plasma free fatty acid (FFA), triglyceride (TG), glucose and insulin levels and increases leptin levels.

Product Specifications for Acipimox

Molecular Weight

154.12

Formula

C6H6N2O3

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

5-Methyl-4-oxide-2-pyrazinecarboxylic acid

CAS Number

51037-30-0

PubChem ID

5310993

InChI Key

DJQOOSBJCLSSEY-UHFFFAOYSA-N

SMILES

CC1=CN=C(C(O)=O)C=[N+]1[O-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 15.41 100
DMSO 15.41 100

Preparing Stock Solutions for Acipimox

The following data is based on the product molecular weight 154.12.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 6.49 mL 32.44 mL 64.88 mL
5 mM 1.30 mL 6.49 mL 12.98 mL
10 mM 0.65 mL 3.24 mL 6.49 mL
50 mM 0.13 mL 0.65 mL 1.30 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

  • Lovisolo Pharmacological proflie of a new antilipolytic agent: 5-methyl-pyrazine-2-carboxylic acid 4-oxide (acipimox) II - Antilipolytic and blood lipid lowering activitiy Pharmacol.Res.Comms.
  • Christie Mechanism of anti-lipolytic action of acipimox in isolated rat adipocytes. Diabetol.
  • Wang-Fisher Acipimox stimulates leptin production from isolated rat adipocytes. J.Endocrinol. 2002 PMID: 12176665

Product Documents for Acipimox

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Acipimox

For research use only

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