Chemical Name: 5-Methyl-4-oxide-2-pyrazinecarboxylic acid
Biological ActivityAntilipolytic agent; lowers plasma free fatty acid (FFA), triglyceride (TG), glucose and insulin levels and increases leptin levels.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Acipimox stimulates leptin production from isolated rat adipocytes.
Wang-Fisher et al.
Pharmacological proflie of a new antilipolytic agent: 5-methyl-pyrazine-2-carboxylic acid 4-oxide (acipimox) II - Antilipolytic and blood lipid lowering activitiy
Lovisolo et al.
Mechanism of anti-lipolytic action of acipimox in isolated rat adipocytes.
Christie et al.
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