Antilipolytic agent; lowers plasma free fatty acid (FFA), triglyceride (TG), glucose and insulin levels and increases leptin levels.
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Acipimox stimulates leptin production from isolated rat adipocytes.
Wang-Fisher et al.
Pharmacological proflie of a new antilipolytic agent: 5-methyl-pyrazine-2-carboxylic acid 4-oxide (acipimox) II - Antilipolytic and blood lipid lowering activitiy
Lovisolo et al.