Chemical Name: 5-Methyl-4-oxide-2-pyrazinecarboxylic acid
Biological ActivityAcipimox is a antilipolytic agent; lowers plasma free fatty acid (FFA), triglyceride (TG), glucose and insulin levels and increases leptin levels.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Acipimox stimulates leptin production from isolated rat adipocytes.
Wang-Fisher et al.
Pharmacological proflie of a new antilipolytic agent: 5-methyl-pyrazine-2-carboxylic acid 4-oxide (acipimox) II - Antilipolytic and blood lipid lowering activitiy
Lovisolo et al.
Mechanism of anti-lipolytic action of acipimox in isolated rat adipocytes.
Christie et al.
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