Chemical Name: 2-[[2-(4-Bromophenyl)-6-methyl-4-pyrimidinyl]amino]ethanol
Biological ActivityAS 1269574 is a GPR119 receptor agonist (EC50 = 2.5 μM in HEK293 cells expressing human GPR119). Enhances insulin secretion stimulated by glucose in vivo. Stimulates proglucagon gene promoter actvity. Orally available.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Identification of a novel GPR119 agonist, AS1269574, with in vitro and in vivo glucose-stimulated Ins secretion.
Yoshida et al.
Stimulation of Proglucagon Gene Expression by Human GPR119 in Enteroendocrine L-cell Line GLUTag.
Chepurny et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for AS 1269574
There are currently no reviews for this product. Be the first to review AS 1269574 and earn rewards!
Have you used AS 1269574?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image