B-HT 920
Chemical Name: 5,6,7,8-Tetrahydro-6-(2-propen-1-yl)-4H-thiazolo[4,5-d]azepin-2-amine dihydrochloride
Purity: ≥98%
Biological Activity
B-HT 920 is a dopamine D2 receptor agonist, α2-adrenoceptor agonist and 5-HT3 receptor antagonist. Displays antiParkinsonian activity.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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In vivo comparisons of the effects of quinpirole and the putative presynaptic DArgic agonists B-HT 920 and SND 919 on striatal DA and acetylcholine release.
Robertson et al.
J.Pharmacol.Exp.Ther., 1993;264:1344 -
5-HT3 receptor blocking properties of the antiParkinsonian agent, talipexole.
Nishio et al.
Gen.Pharmacol., 1996;27:779 -
Adrenoceptor involvement in the cardiovascular responses to B-HT 920 in sinoaortic denervated rats.
Ricci and Taira
Gen.Pharmacol., 1999;32:29 -
A functional fast scan cyclic voltammetry assay to characterize DA D2 and D3 autoreceptors in the mouse striatum.
Maina and Mathews
ACS Chem.Neurosci., 2010;1:450
Product Datasheets
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Citation for B-HT 920
The citations listed below are publications that use Tocris products. Selected citations for B-HT 920 include:
1 Citation: Showing 1 - 1
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Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms.
Authors: Otvos Et al.
Autophagy 2015;7:2336
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