Catalog Number: 2759
Alternate Names: Talipexole
Chemical Name: 5,6,7,8-Tetrahydro-6-(2-propen-1-yl)-4H-thiazolo[4,5-d]azepin-2-amine dihydrochloride
Biological Activity
Dopamine D2 receptor agonist, α2-adrenoceptor agonist and 5-HT3 receptor antagonist. Displays antiParkinsonian activity.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. In vivo comparisons of the effects of quinpirole and the putative presynaptic dopaminergic agonists B-HT 920 and SND 919 on striatal dopamine and acetylcholine release.
    Robertson et al.
    J.Pharmacol.Exp.Ther., 1993;264:1344
  2. Adrenoceptor involvement in the cardiovascular responses to B-HT 920 in sinoaortic denervated rats.
    Ricci and Taira
    Gen.Pharmacol., 1999;32:29
  3. 5-HT3 receptor blocking properties of the antiParkinsonian agent, talipexole.
    Nishio et al.
    Gen.Pharmacol., 1996;27:779
  4. A functional fast scan cyclic voltammetry assay to characterize dopamine D2 and D3 autoreceptors in the mouse striatum.
    Maina and Mathews
    ACS Chem.Neurosci., 2010;1:450

The citations listed below are publications that use Tocris products. Selected citations for B-HT 920 include:

Showing Results 1 - 1 of 1

  1. Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms.
    Authors: Otvos Et al.
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