Catalog Number: 1640
Alternate Names: MEN 10210
Biological Activity
NK2 receptor agonist (pD2 = 6.91). Produces bladder contraction and bronchospasm in guinea pigs in vivo.
Technical Data
  • M.Wt:
    780.93
  • Formula:
    C35H56N8O10S
  • Sequence:
    DSFVALM

    (Modifications: Ala-5 = β-Ala, Met-7 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in 5% NH4OH / water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    122063-01-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Tachykinin NK2 receptors and enhancement of cholinergic transmission in the inflamed rat colon: an in vivo motility study.
    Carini et al.
    Br.J.Pharmacol., 2001;133:1107
  2. A potent and selective agonist for NK-2 tachykinin receptor.
    Rovero et al.
    Peptides, 1989;10:593
  3. In vivo pharmacology of [βAla8]neurokinin A-(4-10), a selective NK-2 tachykinin receptor agonist.
    Maggi et al.
    Eur.J.Pharmacol., 1990;177:81

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