Chemical Name: 2-(3,4-Dihydroxyphenyl)-2-oxoethyl ester thiocyanic acid
Biological Activity BiP (Hsp70-5) ER chaperone inducer; induces BiP expression in vitro and in vivo. Protects against ER-stress induced cell death in neuronal and retinal cell lines. Also protects against ischaemia-induced hippocampal cell death in vivo.
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Store at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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