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BromoCatch™ Ligand, Alkyne

Catalog #: 8940 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
8940/50U

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BromoCatch™ Ligand, Alkyne | BromoCatch Platform
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Description: Clickable alkyne-functionalized covalent probe for BromoCatch-tagged proteins

Chemical Name: (2R)-2-((6S)-4-(4-Acrylamidophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(2-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)ethyl)butanamide

Purity: ≥95%

Product Details
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Biological Activity Technical Data Additional Information Product Datasheets Calculators

Biological Activity

BromoCatch™ Ligand, Alkyne is a covalent ligand engineered to irreversibly bind BromoCatch-tagged proteins via selective reaction with the E438C cysteine mutant of the Brd4-BD2 domain. Featuring a terminal alkyne appended to the BromoCatch Ligand scaffold, this ligand enables downstream modification through copper-catalyzed azide-alkyne cycloaddition (CuAAC). BromoCatch™ Ligand, Alkyne facilitates modular tagging of BromoCatch fusions with fluorophores, biotin, affinity tags, or functional moieties, offering a flexible platform for custom probe development. It enables site-specific protein labeling in vitro and is ideal for applications in chemical biology, proteomics, and multiplexed detection assays.

Please refer to this protocol for further information on how to use this product.

BromoCatch™ is a trademark of Bio-Techne Corp.

Technical Data

M.Wt:
632.78
Formula:
C33H40N6O5S
Purity:
≥95%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under exclusive licence from the University of Dundee

Product Datasheets

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Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.