Chemical Name: 3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indole-5-carboxylic acid hydrochloride
Biological ActivitySelective, peripherally acting dopamine D2 receptor agonist. Modulates noradrenalin release and sympathetic activation. Displays antihypertensive properties in vivo.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Pharmacological basis for antihypertensive therapy with a novel DA agonist
Haeusler et al.
Eur.Heart J., 1992;13:129
DA receptor modulation of noradrenaline release by carmoxirole in human cortical kidney slices.
Rump et al.
Neurochemical profile of EMD 45609 (carmoxirole), a DA DA2-receptor agonist.
Hasse et al.
Citations for Carmoxirole hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Carmoxirole hydrochloride include:
2 Citations: Showing 1 - 2
Hypothyroidism affects D2 receptor-mediated breathing without altering D2 receptor expression.
Authors: Schlenker Et al.
Respir Physiol Neurobiol 2014;193:29
Hypothyroidism stimulates D2 receptor-mediated breathing in response to acute hypoxia and alters D2 receptors levels in carotid bodies and brain.
Authors: Schlenker and Schultz
Respir Physiol Neurobiol 2012;180:69
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