CDP 840 hydrochloride
Chemical Name: 4-[(2R)-2-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-phenylethyl]-pyridine hydrochloride
Biological ActivityCDP 840 hydrochloride is a potent and selective inhibitor of phosphodiesterase (PDE) 4 (IC50 = 12 nM for native PDE4). Competitively inhibits all PDE4 isoenzymes (IC50 values are 4, 9, 9 and 45 nM for PDE4A, PDE4B, PDE4C and PDE4D human recombinant isoforms expressed in yeast).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
The inhibition of antigen-induced eosinophilia and bronchoconstriction by CDP840, a novel stereo-selective inhibitor of phosphodiesterase type 4.
Hughes et al.
A comparison of the inhibitory activity of PDE4 inhibitors on leukocyte PDE4 activity in vitro and eosinophil trafficking in vivo.
Cooper et al.
CDP840: a novel inhibitor of PDE-4.
Perry et al.
Cell Biochem.Biophys., 1998;29:113
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for CDP 840 hydrochloride
There are currently no reviews for this product. Be the first to review CDP 840 hydrochloride and earn rewards!
Have you used CDP 840 hydrochloride?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image