Chemical Name: 3-[(2E)-3-(4-Methoxyphenyl)-1-oxo-2-propen-1-yl]-6-methyl-4-phenyl-2(1H)-quinolinone
Biological ActivityCeramidase inhibitor; inhibits proliferation in SKOV3 ovarian carcinoma cells (IC50 = 3.9 μM). Induces accumulation of ceramide species and decreases sphingosine and sphingosine-1-phosphate (S1P) levels in SKOV3 cells.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Discovery and evaluation of inhibitors of human ceramidase.
Draper et al.
Mol. Cancer Ther., 2011;10:2052
Citation for Ceranib 1
The citations listed below are publications that use Tocris products. Selected citations for Ceranib 1 include:
1 Citation: Showing 1 - 1
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for Ceranib 1
There are currently no reviews for this product. Be the first to review Ceranib 1 and earn rewards!
Have you used Ceranib 1?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image