CGH 2466 dihydrochloride

Catalog # Availability Size / Price Qty
2344/10
2344/50
CGH 2466 dihydrochloride | CAS No. 1177618-54-0 | Non-selective Adenosine Receptor Antagonists
1 Image
Description: A1, A2B and A3 antagonist and inhibitor of p38 MAPK and PDE4

Chemical Name: 4-(3,4-Dichlorophenyl)-5-(4-pyridinyl)-2-thiazolamine dihydrochloride

Purity: ≥99%

Product Details
Citations (1)
Supplemental Products
Reviews

Biological Activity

Adenosine A1, A2B and A3 receptor antagonist (IC50 values are 19, 21, and 80 nM respectively). Also inhibits p38 MAPK (IC50 = 187 - 400 nM) and phosphodiesterase type 4D (IC50 = 22 nM). Displays potent anti-inflammatory effects in vitro and in vivo. Potentially useful for asthma and chronic obstructive pulmonary disease (COPD) research.

Technical Data

M.Wt:
395.13
Formula:
C14H9N3SCl2.2HCl
Solubility:
Soluble to 10 mM in DMSO with gentle warming and to 5 mM in ethanol
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
1177618-54-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citation for CGH 2466 dihydrochloride

The citations listed below are publications that use Tocris products. Selected citations for CGH 2466 dihydrochloride include:

1 Citation: Showing 1 - 1

  1. An Adenosine Receptor for Olfaction in Fish.
    Authors: Wakisaka Et al.
    Curr Biol  2017;27:1437

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for CGH 2466 dihydrochloride

There are currently no reviews for this product. Be the first to review CGH 2466 dihydrochloride and earn rewards!

Have you used CGH 2466 dihydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.