CGH 2466 dihydrochloride
Chemical Name: 4-(3,4-Dichlorophenyl)-5-(4-pyridinyl)-2-thiazolamine dihydrochloride
Biological ActivityCGH 2466 dihydrochloride is an adenosine A1, A2B and A3 receptor antagonist (IC50 values are 19, 21, and 80 nM respectively). Also inhibits p38 MAPK (IC50 = 187 - 400 nM) and phosphodiesterase type 4D (IC50 = 22 nM). Displays potent anti-inflammatory effects in vitro and in vivo. Potentially useful for asthma and chronic obstructive pulmonary disease (COPD) research.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
CGH2466, a combined adenosine receptor antagonist, p38 mitogen-activated protein kinase and phosphodiesterase type 4 inhibitor with potent in vitro and in vivo anti-inflammatory activities.
Trifilieff et al.
Citation for CGH 2466 dihydrochloride
The citations listed below are publications that use Tocris products. Selected citations for CGH 2466 dihydrochloride include:
1 Citation: Showing 1 - 1
An Adenosine Receptor for Olfaction in Fish.
Authors: Wakisaka Et al.
Curr Biol 2017;27:1437
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