CID 2011756

Catalog # Availability Size / Price Qty
4644/10
4644/50
Cat.No. 4644 - CID 2011756 | C22H21ClN2O3 | CAS No. 638156-11-3
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Description: Pan protein kinase D (PKD) inhibitor; cell permeable

Chemical Name: 5-(3-Chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide

Product Details
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Biological Activity

Protein kinase D (PKD) inhibitor (IC50 values are 0.6, 0.7 and 3.2 μM for PKD2, PKD3 and PKD1 respectively). Cell permeable (EC50 = 10 μM for PKD1 inhibition). ATP-competitive.

Technical Data

Formula:
C22H21ClN2O3
Solubility:
Soluble to 50 mM in DMSO
Storage:
Store the unopened product at room temperature. Do not use past expiration date.
CAS No:
638156-11-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Background References

  1. Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity.
    Sharlow et al.
    PLoS One, 2011;6:e25134

Product Datasheets

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