Protein kinase D (PKD) inhibitor (IC50
values are 0.6, 0.7 and 3.2 μ
M for PKD2, PKD3 and PKD1 respectively). Cell permeable (EC50
= 10 μ
M for PKD1 inhibition). ATP-competitive.
Soluble to 50 mM in DMSO
Store at RT
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity.
Sharlow et al.
PLoS One, 2011;6:e25134