Chemical Name: N-[2-[[3-(Dimethylamino)propyl]thio]phenyl]-3-phenyl-2-propenamide hydrochloride
Biological ActivityCinanserin hydrochloride is a 5-HT2 antagonist. Also inhibits 3C-like proteinase (3CLpro; Mpro). Inhibits replication of SARS-CoV.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Receptor binding profile of R-41-468, a novel antagonist at 5HT2 receptors.
Leysen et al.
Life Sci., 1981;28:1015
Molecular structure basis of ligand selectivity for 5-HT2 versus 5-HT1C cortical receptors.
Pierce et al.
Naunyn Schmiedebergs Arch.Pharmacol., 1992;346:4
Cinanserin is an inhibitor of the 3C-like proteinase of the severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro.
Chen et al.
Citations for Cinanserin hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Cinanserin hydrochloride include:
3 Citations: Showing 1 - 3
Tryptophan hydroxylase 1 and 5-HT7 receptor preferentially expressed in triple-negative breast cancer promote cancer progression through autocrine serotonin signaling.
Authors: Gautam Et al.
Mol Cancer 2016;15:75
A putative 'pre-nervous' endocannabinoid system in early echinoderm development.
Authors: Buznikov Et al.
Dev Neurosci 2010;32:1
Frequency-dependent modulation of retinogeniculate transmission by serotonin.
Authors: Seeburg Et al.
J Neurosci 2004;24:10950
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