Cinnabarinic acid

   
Product Datasheet
Catalog Number:4119
Chemical Name:2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid
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Biological Activity
mGlu4 receptor agonist. Activates mGlu4 receptors in transiently transfected HEK293 cells; selective over all other mGlu subtypes (mGlu1, mGlu2 and mGlu5-8). Decreases cAMP levels in native cultured cerebellar granule cells. Also counteracts excitotoxic neuronal cell death induced by NMDA in mixed cultures of cortical cells; displays neuroprotective activity.
Technical Data
  • M.Wt:
    300.22
  • Formula:
    C14H8N2O6
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    606-59-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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