Clofibric acid
Discontinued Product
0825 has been discontinued.
View all Non-selective PPAR Receptor Agonists products.
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Description: PPAR agonist
Chemical Name: 2-(4-Chlorophenoxy)-2-methylpropanoic acid
Biological Activity
Clofibric acid is a PPAR agonist. Antihyperlipoproteinemic.Technical Data
M.Wt:
214.65
Formula:
C10H11ClO3
Solubility:
Soluble to 100 mM in 1eq. NaOH
Storage:
Store at RT
CAS No:
882-09-7
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Peroxisome proliferator-activated receptors in the cardiovascular system.
Bishop-Bailey
Br.J.Pharmacol., 2000;129:823 -
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ.
Forman et al.
Proc.Natl.Acad.Sci.U.S.A., 1997;94:4312 -
Mechanism of action of fibrates.
Shepherd
Postgrad.Med.J., 1993;69:S34
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