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Product Details
Supplemental Products
Reviews
Biological Activity
NR2B-selective, competitive antagonist of the NMDA receptor. Blocks NMDA-evoked current in mouse cortical neurons (IC50 = 480 nM); also inhibits NMDA-evoked responses in oocytes expressing N2RB, but not NR2A, subunits (IC50 ~300 nM). Exhibits neuroprotective properties in vivo and in vitro.
NR2B-selective, competitive antagonist of the NMDA receptor. Blocks NMDA-evoked current in mouse cortical neurons (IC50 = 480 nM); also inhibits NMDA-evoked responses in oocytes expressing N2RB, but not NR2A, subunits (IC50 ~300 nM). Exhibits neuroprotective properties in vivo and in vitro.
Technical Data
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M.Wt:2264.21
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Formula:C88H138N26O44
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Sequence:GEXXLQXNQXLIRXKSN
(Modifications: X = Gla, Asn-17 = C-terminal amide)
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Solubility:Soluble to 1 mg/ml in water
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Storage:Store at -20°C
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CAS No:93438-65-4
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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