CP 135807

Key Product Details

Product Description

Selective 5-HT_1D receptor agonist. Produces dose-dependent decreases in extracellular 5-HT concentration.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Product Specifications for CP 135807

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for CP 135807

The following data is based on the product molecular weight 351.40.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.85 mL	14.23 mL	28.46 mL
5 mM	0.57 mL	2.85 mL	5.69 mL
10 mM	0.28 mL	1.42 mL	2.85 mL
50 mM	0.06 mL	0.28 mL	0.57 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Mansbach CP-135,807, a selective 5-HT1D agonist: effects in drug discrimination and punishment procedures in the pigeon. Psychopharmacology 1996 PMID: 8972551
• Rollema Combined administration of a 5-hydroxytryptamine (5-HT)_1D antagonist and a 5-HT reuptake inhibitor synergistically increases 5-HT release in guinea pig hypothalamus in vivo. J.Neurochem. 1996 PMID: 8863532
• Hertel The antipsychotic drug risper. interacts with auto- and hetero-receptors regulating serotonin output in the rat frontal cortex. Neuropharmacology 1999 PMID: 10462130

Product Documents for CP 135807