CP 471474

  ( 3 citations )    
Product Datasheet
Catalog Number:3780
Chemical Name:2-[[[4-(4-Fluorophenoxy)phenyl]sulfonyl]amino]-N-hydroxy-2-methylpropanamide
Product Details
Citations (3)
Reviews
Biological Activity
Broad spectrum MMP inhibitor (IC50 values are 0.7, 0.9, 13, 16 and 1170 nM for MMP-2, MMP-13, MMP-9, MMP-3 and MMP-1 respectively). Attenuates early left ventricular dilation after experimental myocardial infarction in mice.
Technical Data
  • M.Wt:
    368.38
  • Formula:
    C16H17FN2O5S
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >97
  • Storage:
    Store at -20°C
  • CAS No:
    210755-45-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for CP 471474 include:

3 Citations: Showing 1 - 3
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  1. Cleavage/Alteration of interleukin-8 by matrix metalloproteinase-9 in the female lower genital tract.
    Authors: Zariffard Et al.
    PLoS One  2015;10:e0116911
  2. Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.
    Authors: Brafman Et al.
    PLoS One  2013;20:369
  3. MMP13 mediates cell cycle progression in melanocytes and melanoma cells: in vitro studies of migration and proliferation.
    Authors: Meierjohann Et al.
    Mol Cancer  2010;9:201

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