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CP 471474

3780 3 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3780/10
3780/50
CP 471474 | CAS No. 210755-45-6 | Synthetic Metalloprotease Inhibitors
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Description: Broad spectrum MMP inhibitor

Chemical Name: 2-[[[4-(4-Fluorophenoxy)phenyl]sulfonyl]amino]-N-hydroxy-2-methylpropanamide

Purity: ≥97%

Product Details
Citations (3)
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

CP 471474 is a broad spectrum MMP inhibitor (IC50 values are 0.7, 0.9, 13, 16 and 1170 nM for MMP-2, MMP-13, MMP-9, MMP-3 and MMP-1 respectively). Attenuates early left ventricular dilation after experimental myocardial infarction in mice.

Technical Data

M.Wt:
368.38
Formula:
C16H17FN2O5S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥97%
Storage:
Store at -20°C
CAS No:
210755-45-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.

Product Datasheets

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Citations for CP 471474

The citations listed below are publications that use Tocris products. Selected citations for CP 471474 include:

3 Citations: Showing 1 - 3

  1. Cleavage/Alteration of interleukin-8 by matrix metalloproteinase-9 in the female lower genital tract.
    Authors: Zariffard Et al.
    PLoS One  2015;10:e0116911
  2. Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.
    Authors: Brafman Et al.
    PLoS One  2013;20:369
  3. MMP13 mediates cell cycle progression in melanocytes and melanoma cells: in vitro studies of migration and proliferation.
    Authors: Meierjohann Et al.
    Mol Cancer  2010;9:201

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